Microarrays in biology and medicine

Microarrays coming of age in cardiovascular medicine: standards, predictions, and biology.

Applications of DNA microarrays in biology.

DNA microarrays have enabled biology researchers to conduct large-scale quantitative experiments. This capacity has produced qualitative changes in the breadth of hypotheses that can be explored. In what has become the dominant mode of use, changes in the transcription rate of nearly all the genes in a genome, taking place in a particular tissue or cell type, can be measured in disease states, ...

Protein microarrays for personalized medicine.

BACKGROUND Over the last 10 years, DNA microarrays have achieved a robust analytical performance, enabling their use for analyzing the whole transcriptome or for screening thousands of single-nucleotide polymorphisms in a single experiment. DNA microarrays allow scientists to correlate gene expression signatures with disease progression, to screen for disease-specific mutations, and to treat pa...

Ultrasound in Medicine and Biology

To assess the comparability of ultrasonographic (US) subcutaneous fat thickness (SFT) measurements in comparison with computed tomography (CT) at reference points (RPs) representative of HIV related adipose redistribution syndrome (HARS) in patients treated with antiretrovirals. US and CT measurements were compared in nine patients with clinical reports of HARS. We obtained the best resolution ...

Isoenzymes in Biology and Medicine

formidable problems. Much of the value of the analysis may be lost in the synthesis. For example, in his effort to deal comprehensively yet concisely with similar but not identical investigations the author may create such monsters as: Allegedly, it is possible to induce phenomenon X, by administration of substance Y in the rabbit (1-3) but not in the rat (3-5); however, these claims have been ...